How to Use: BIOEFFECT HYDRATION CREAM: Apply to face, neck, and décolleté, massaging gently in an upwards motion. A great addition to the BIOEFFECT skincare routine, as it can be used day and night, alone and on top of BIOEFFECT serums for added hydration and nourishment.BIOEFFECT OSA WATER MIST: Close your eyes and apply 2-3 sprays to your face and neck. Let absorb, and gently blot excess with a clean tissue if necessary. Use as often as desired to refresh and rebalance your skin. A great addition to the BIOEFFECT skincare routine, as the EGF protein in our serums performs best in a moisture-rich environment.